Team:Jefferson VA SciCOS

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Established in 1985, Thomas Jefferson High School for Science and Technology is the result of a partnership of businesses and schools created to improve education in science, mathematics, and technology. Representatives from business and industry and staff of the Fairfax County Public Schools worked together in curriculum and facilities development for the school. In recent years, local business leaders and Jefferson parents have formed the Jefferson Partnership Fund to help raise money to maintain and equip labs and classrooms in the school. As the Governor's School for Science and Technology in Northern Virginia, the school is also supported by the Virginia Department of Education. In addition to providing a specialized education for selected students in Fairfax County, Jefferson also serves other school districts including Arlington, Loudoun, and Prince William counties as well as the cities of Fairfax and Falls Church.
Established in 1985, Thomas Jefferson High School for Science and Technology is the result of a partnership of businesses and schools created to improve education in science, mathematics, and technology. Representatives from business and industry and staff of the Fairfax County Public Schools worked together in curriculum and facilities development for the school. In recent years, local business leaders and Jefferson parents have formed the Jefferson Partnership Fund to help raise money to maintain and equip labs and classrooms in the school. As the Governor's School for Science and Technology in Northern Virginia, the school is also supported by the Virginia Department of Education. In addition to providing a specialized education for selected students in Fairfax County, Jefferson also serves other school districts including Arlington, Loudoun, and Prince William counties as well as the cities of Fairfax and Falls Church.
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Revision as of 19:18, 4 April 2013


Background


Established in 1985, Thomas Jefferson High School for Science and Technology is the result of a partnership of businesses and schools created to improve education in science, mathematics, and technology. Representatives from business and industry and staff of the Fairfax County Public Schools worked together in curriculum and facilities development for the school. In recent years, local business leaders and Jefferson parents have formed the Jefferson Partnership Fund to help raise money to maintain and equip labs and classrooms in the school. As the Governor's School for Science and Technology in Northern Virginia, the school is also supported by the Virginia Department of Education. In addition to providing a specialized education for selected students in Fairfax County, Jefferson also serves other school districts including Arlington, Loudoun, and Prince William counties as well as the cities of Fairfax and Falls Church.

Jefferson VA SciCOS logo colored.png

Abstract


Domoic acid is an organic acid found in algal blooms and shellfish, and is produced by dinoflagellates. This organic acid is a neurotoxin that is both responsible for seafood poisoning and red tide fish kills. Its chemical structure includes kainic acid, a relatively harmless organic acid derivative of the amino acid proline. Currently, ELISAs for domoic acid test false positives when in contact with kainic acid; this causes safe seafood to be thrown away due to concerns of domoic acid tainting. Moreover, E.coli bacteria can degrade and live off of L-proline.

The purpose of this project is to bioengineer E.coli, using the codon for L-proline degradation, to degrade and detect domoic acid, as well as educating the general public about the risks of domoic acid poisoning and the positive and negative externalities of bioengineering.

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             Domoic Acid              

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             Proline              
Transparent.pngTransparent.pngTransparent.pngTransparent.pngDomoicAcid.pngTransparent.pngTransparent.pngTransparent.pngTransparent.pngL-proline-2D-skeletal.png