Team:TPHS SanDiego/Project

From 2013hs.igem.org

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<html>
<html>
-
<html lang="en">
 
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<style = "text/css" media="screen">
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<div id="top-section3"><center><img src="https://static.igem.org/mediawiki/2013hs/3/35/TorrePinesNavigation%28Tareq%29.jpg" alt="header" border="0"  usemap="#igemmap" width="1000"></center></div>
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<map name="igemmap">
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 +
<div class="layout-1000">
 +
<div class="row">
 +
<div class="col12" >
 +
<ul class="topnav">
 +
    <li><a href="https://2013hs.igem.org/Team:TPHS_SanDiego">Home  </a></li>
 +
    <li>
 +
        <a href="https://2013hs.igem.org/Team:TPHS_SanDiego/Project">Project</a>
 +
    </li>
 +
    <li>
 +
        <a href="https://2013hs.igem.org/Team:TPHS_SanDiego/Parts">Parts</a>
 +
    </li>
 +
    <li><a href="https://2013hs.igem.org/Team:TPHS_SanDiego/Safety">Safety</a></li>
 +
    <li><a href="https://2013hs.igem.org/Team:TPHS_SanDiego/Team">Team</a></li>
 +
    <li><a href="https://2013hs.igem.org/Team:TPHS_SanDiego/Protocols">Protocols</a></li>
 +
    <li><a href="https://2013hs.igem.org/Team:TPHS_SanDiego/Journal">Journal</a></li>
 +
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* http://www.opensource.org/licenses/mit-license.php
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* jQuery Nivo Slider v2.6
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* http://nivo.dev7studios.com
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*
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* Copyright 2011, Gilbert Pellegrom
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* Free to use and abuse under the MIT license.
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-
* http://www.opensource.org/licenses/mit-license.php
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*
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* March 2010
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*/
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Our project focuses on promoter engineering. Our goal is to characterize a set of promoters (of our design) by moving the repressor and/or activator binding sites with respect to the -10 and -35 regions of the promoter. Ideally, we would like to show that by moving an activator binding site it can become a repressor and that by moving a repressor binding site it may become either irrelevant to transcription rate or even boost it. We also want to see if there is a steep decline in repressor/activator function as the binding site move along the promoter or if it is a gradual/linear change. We believe this project could have application to genetic circuits by allowing a single protein to either activate or repress a promoter depending on where the binding sites are placed on the promoter.
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Latest revision as of 23:21, 21 June 2013

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Mercury

     

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