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Team:St Pauls London/Human Practices
From 2013hs.igem.org
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The schools in attendance were: | The schools in attendance were: | ||
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Germany | Germany | ||
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Otto von Taube Gymnasium | Otto von Taube Gymnasium | ||
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Japan | Japan | ||
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Gojo Senior High School | Gojo Senior High School | ||
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Handa Senior High School | Handa Senior High School | ||
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Ichinomiya High School | Ichinomiya High School | ||
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Jishukan High School | Jishukan High School | ||
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Koh High School | Koh High School | ||
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Meiwa Senior High School | Meiwa Senior High School | ||
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Okazaki-kita Senior High School | Okazaki-kita Senior High School | ||
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Seisho Senior High School | Seisho Senior High School | ||
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Toyohashi Higashi Senior High School | Toyohashi Higashi Senior High School | ||
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Toyota Nishi Senior High School | Toyota Nishi Senior High School | ||
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Yokosuka High School | Yokosuka High School | ||
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Yutakagaoka High school | Yutakagaoka High school | ||
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Zuiryo Senior High School | Zuiryo Senior High School | ||
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United Kingdom | United Kingdom | ||
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Hammersmith Academy | Hammersmith Academy | ||
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King’s School Canterbury | King’s School Canterbury | ||
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Latymer Upper School | Latymer Upper School | ||
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Radley College | Radley College | ||
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Simon Langton Grammar School | Simon Langton Grammar School | ||
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St Paul’s School | St Paul’s School | ||
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St Paul’s Girls’ School | St Paul’s Girls’ School | ||
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Westminster School | Westminster School | ||
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William Morris Sixth Form | William Morris Sixth Form | ||
Revision as of 12:26, 7 June 2013
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Human Practices
The Project's Impact
Our team is aiming to create a semi-quantitative detector for lactose, a sugar molecule which causes intolerance in 9% of Caucasians, and between 70-90% of Asians, South Americans and Africans. It is most commonly found in milk and dairy products, and intolerance has been linked to recent over-consumption of milk and dairy, particularly in Europe and North America.
Individuals who are lactose intolerant have an insufficient lactase enzyme concentration in their digestive tract, so they are unable to hydrolyse lactose into galactose and glucose. As a result these disaccharide lactose molecules pass straight through the small intestine and into the colon. Bacteria in the colon are able to hydrolyse and then metabolise lactose, and their anaerobic respiration of lactose produces CO2 and CH4 in the colon. This leads to the bloated feeling and symptoms associated with intolerance. Unabsorbed glucose and galactose monosaccharides in the colon also reduce water potential in the colon, leading to an inflow of water, and hence diarrhea. You can read more about lactose intolerance from the [http://www.milk.co.uk/page.aspx?intPageID=59| UK Dairy Council].
We hope to go some way to fix this problem by providing a biological lactose detector. This will enable lactose intolerants to better decide what food produce to eat, and help them avoid painful symptoms of intolerance. Furthermore, the semi-quantitative nature of the project will enable people with a range of different tolerance levels to be catered for by the sensor; individuals with higher lactose tolerance are able to eat more lactose-rich food, but individuals with low tolerance are able to avoid it altogether. Our hope is that this detector may be used in laboratory setting by food manufacturers to test and correctly label produce for consumers - this will help to properly inform the public and allow them to make better health choices.
Outreach and Informing People
Our team presented this project at the second annual [http://www.stpaulsschool.org.uk/news/academic-news/anglo-japanese-international-science-conference Anglo-Japanese Science Conference for Students] at St Paul's School in March. There were schools from around the UK, several Japanese Academies and a German Gymnasium in attendance. The conference was designed to raise awareness about different scientific projects that school students are doing; we gave a 15 minute presentation on our progress and plans, and took questions from the audience afterwards. For the vast majority of the students this was the first that they had heard of the iGEM competition and many people fielded questions about the project and how they might be able to compete in the future at high school or collegiate level.
The schools in attendance were:
Germany
Otto von Taube Gymnasium
Japan
Gojo Senior High School
Handa Senior High School
Ichinomiya High School
Jishukan High School
Koh High School
Meiwa Senior High School
Okazaki-kita Senior High School
Seisho Senior High School
Toyohashi Higashi Senior High School
Toyota Nishi Senior High School
Yokosuka High School
Yutakagaoka High school
Zuiryo Senior High School
United Kingdom
Hammersmith Academy
King’s School Canterbury
Latymer Upper School
Radley College
Simon Langton Grammar School
St Paul’s School
St Paul’s Girls’ School
Westminster School
William Morris Sixth Form
